Application: iFOUR Dispensing system of M2-Instruments for SPRi-based applications
The Laboratory of Nanomedicine and Clinical Biophotonics (LABION - www.labion.eu) at Fondazione Don Carlo Gnocchi in Milan (Italy) is working on the implementation of a Surface Plasmon Resonance imaging (SPRi) platform for the analysis of natural and synthetic nano-sized particles, such as extracellular vesicles and liposomes.
A.Extracellular vesicles (EVs) are lipid-bilayer delimited nanoparticles naturally released from all cell types and found in different body fluids. They have a complex biochemical composition containing proteins, lipids, RNA and DNA with a specific molecular signature of the cells from which they originated. EVs are studied as potential biomarkers as they can change their composition and concentration according to the physio-pathological state of the cell of origin.