Announcement: 26thof January 2024

AIT logo

M24You GmbH, the exclusive global distributor of M2-Automation technology, is excited to announce its new cooperation with AIT, the Austrian Institute of Technology. The AIT (Austrian Institute of Technology) is Austria’s largest applied research institute. The collaboration between M24You GmbH and AIT represents an exciting opportunity for both companies to combine their expertise and solutions, resulting in the delivery of even more innovative approaches to the customers.

Within the AIT, the Competence Unit Molecular Diagnostics is at the forefront of developing cutting-edge technologies and innovative methods for non-invasive and minimally invasive diagnostics. The focus spans from mass-fabricable and cost-effective biosensing systems for point-of-need applications to biomarker discovery, assay design, bioinformatics, and customized analysis.

In the field of biosensor development, AIT addresses pivotal – firstly, how to bring a certain desired functionality to a sensor surface or microfluidic, and secondly, how to establish scalable fabrication processes for precise and reproducible modification of surfaces, such as electrodes in electrochemical sensors.

To bring assays to the surface, the AIT develops (bio)inks based on nanozymes, enzymes, nucleic acids, antibodies, aptamers, and redox-active or ion-selective compounds, having resource and environmentally-friendly material and processes. A pivotal aspect of product development involves seamlessly transitioning the assay from a laboratory scale to small-batch production.

To meet this demand, AIT is equipped with state-of-the-art non-contact liquid handling systems, including the M2-Automation iONE-600 instrument, known for its precision in position (±3 µm) and volume control (SD 3-5%). The dispenser enables the modification of substrates up to A3 size under a controlled atmosphere, ensuring reproducibility (humidifier, temperature control, ionizer, DEW-point) and efficiency. Its pico- and nanoliter dispensing units allow precise modification of target structures (dimensions of 100 µm up to mm-scale) with (bio)ink volumes ranging from 100 pL to mL. The creation of dispensing patterns for 2D and 3D substrates is facilitated by a DXF file importer. Efficient processing of sensor and microfluidic foils is achieved through fast axes movement and fiducial reference marker recognition. Quality control is of paramount importance and AIT employs a range of methods (light microscopy, SEM, EDX, electrochemical testing) to ensure process integrity and accuracy.

Join AIT in setting new standards in molecular diagnostics, where innovation meets precision, sustainability, and excellence.

Trust M24You to deliver personalized, cutting-edge microarray instruments from R&D to full-scale automated production lines.

iONE_AIT 

 

 

Announcement: 22ndof June 2022

We would like to thank Prof. Dr. Yong-Ak (Rafael) Song for sharing his application within New York University Abu Dhabi. Prof. Rafael Song is an Assistant Professor of Mechanical and Biomedical Engineering New York University Abu Dhabi, Division of Engineering Micro- and Nanoscale Bioengineering Research Group. Prof. Song's research and teaching interests are interdisciplinary in both mechanical engineering disciplines such as design and manufacturing of MEMS devices, fluid mechanics, and micro/nanofabrication, as well as in biological engineering areas such as BioMEMS for point-of-care diagnostics, neuroprosthetic implants, high-throughput screening and optogenetics.

Read the application.

 

 

 

 

Announcement: 1stof June 2022

 

We are proud to announce, that the new iONE-1200 system was successfully installed at Innobiochips for improving the quality and production capacity. The system is equipped with M2 dispensing technology for higher speed and improved accuracy, compare to the traditional technologies.

Innobiochips is a French IVD company committed to bring deep innovations on the IVD market. Innobiochips is specialized in the development of innovative multiplex immunoassays and aims to position its technology, SirYus™, as a new standard for In Vitro Diagnostics.

Read more about multiplex immunoassay SirYus in application section.

 

 

 

 

 

Announcement: 16th of March 2022

 

We proudly announce that Pictor Ltd, an invitro diagnostic company based in Auckland, New Zealand, is using dispensing technology of M2-Automation for manufacturing their high-quality immunodiagnostics microarrays. On the photo there is Mrs. Dr. Jimena Tejerina, Senior Scientist of Pictor Ltd at the high-speed precision iONE-1200 manufacturing system. Find more information about Pictor’s immunodiagnostic products at www.Pictor.com and the latest product application on our website in the link https://www.m24you.com/nanoarray/.

iONE-1200

 

 

 

Announcement: 15th of June 2021

RESISTOVAC is one of the six lead projects in the second BMBF funding phase at the InfectoGnostics Research Campus Jena from 2020 to 2025. The aim of the project is to develop a laboratory-independent diagnostic system for the rapid and cost-effective determination of vaccination status and bacterial resistance factors. This involves the development of multiparameter tests, where a large number of measurement results can be determined in parallel with a single sample in a single test. 

RESISTOVAC – Schnelle & ökonomische Bestimmung des Immunstatus & bakterieller Resistenzfaktoren

Related projects to Inter-Array developments

Announcement: 2nd of June 2021

BiFlow Systems and M24You expand their collaboration

BiFlow

M24You and BiFlow Systems expand collaboration in manufacturing microfluidic IVD test kits at the highest quality level

June 2, 2021 | News room

BiFlow and M24You alliance underpins commitment to increase manufacturing availability for microfluidic rapid diagnostic testing

  • After many years of close collaboration both parties agreed for a joint activity in massive scaling-up the qualified manufacturing process under ISO9001/13485
  • In combination with state of the art manufacturing technology from M2-Automation with high precision dispensing technology to enable BiFlow to scale-up microfluidic (microarray) manufacturing across the business 
  • Joint activities will include co-working at BiFlow Systems, Chemnitz (Germany), and at M2/ M24You GmbH, headquarters in Berlin (Germany)

 

Chemnitz and Berlin, Germany, June 2, 2021:   Today BiFlow announced an important step in collaborating and selecting M24You as their technology provider and science partner for this effort. M2-Automation/ M24You manufactures and supply full Automated High Precision Liquid Handling systems for the microfluidic IVD production process, scalable from R&D up Production for accelerating your development into diagnostic availability for global purposes.

M2-Automation’s key technology within Next-Generation High Precision Liquid Handling for diagnostic production platform allowing customers to operate within one system on different volume levels (picolitre, nanolitre, microlitre or millilitre) for ultimate high throughput manufacturing freedom, with real target recognition, dispensing process viewing or inline QC with auto-corrective sub-routines for perfectly produced diagnostics.

Dr. Jörg Nestler, Director of BiFlow Systems said: Since more than a decade we have been working on integrated microfluidic solutions for diagnostic applications. During the last years, we mainly focused on the amplification and the multi-parameter detection of DNA and RNA using fluorescence microarrays. With such microarrays it is possible– for example – to identify different bacterial species, antibiotic resistances or different viruses. To provide an even more complete solution for our customers we were looking for a certified partner with strong expertise in spotting technologies as well on microarray readout. With M24You we found an ideal partner for our future upscaling of manufacturing and for the joint development of new diagnostic solutions.Mr. Ron Wolbert, MSc., Director of M24You GmbH, added: “Our strategic alliance will combine BiFlow’s expertise powered by M2-Automation’s ultra-precision liquid handing technology within iFOUR, iTWO, iONE- or iZERO-platforms and tackles the biggest challenges mankind is facing: “advanced multiplexing with the goal of improvement the healthcare worldwide”.

For more information or arranging interviews, please contact: info@biflow-systems.com or info@M24You.com

About BiFlow Systems

BiFlow Systems is specialized in transferring complex diagnostic assays into small, chipcard-sized cartridges. This is achieved by a special, fully integrated pumping, heating and valving technology. The company provides both, standard cartridges for evaluation and research purposes, as well as customized cartridges for various applications and customers. Only a tiny instrument is required to operate such self-contained cartridges. Due to the multiple functionalities which can be integrated into those cartridges the technology is well suited for various types of assays, such as DNA/RNA-based assays, cell-based assays or protein-based assays. More details are available on www.biflow-systems.com, or more dedicated to microarray applications on
 https://applications.biflow.systems/microarrays.

About M24You

M24You is the strategic partner of M2-Automation and act as the exclusive global sales partner of M2-Automation products. M24You provides solutions for ultrafast and precise liquid handling for research and development, production and contract manufacturing. We support our customers not only with a small dispensing platform, dedicated for research, but also with instruments dedicated for small, middle and high production levels. We enable you with complete equipment from microdispensing instruments till microarray readers for your application request.  Video with our state-of-the-art technology is visible at: www.M24You.com

M2-Automation, the manufacturer of this unique Next-Generation High Precision Liquid Handling systems, was founded in 2003 in Berlin, Germany. From the beginning, the company has been focused on production of various micro-dispensers, from pico- till microlitre volume ranges, with the highest possible accuracy. The M2-Automation instruments can handle thousands of samples within 24 hours by the choice in between contact and non-contact dispensing approach, and are suitable for proteins, peptides, antibodies, DNA, glycans, cells, polymers, etc. on different targets like microtiter plates, microfluidics, CMOS or nitrocellulose with Spot on the Fly dispensing technology (3200 spots/sec). Many instruments are modular produced and adapted to our customer specifications and specific application requests. Don’t hesitate to contact us directly or via our distributors. More information can be found on our website: www.m24you.com

Contact:  

M2-Automation/ M24You GmbH, Bessemerstr. 16, 12103 Berlin, Germany, www.M24You.com
 or info@M24You.com

 

Announcement:10th of May 2021

Macro Array Diagnostics GmbH, MADx, is a Vienna based MedTech company, which develops, produce and distributes rapid tests, instruments and software for allergy diagnostics and research applications. Their products allow flexible, reliable and affordable sensitization profiling of each patient.

MADx produce their tests with M2-Automation Technology and uses the iONE-1200 MultiChannel system for cost effective production. The video is illustrating production process and acceleration of the iONE-1200 system and dispensing accuracy in nanoliter volume range.